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Target
Heme oxygenase 2
Ligand
BDBM50207199
Substrate
n/a
Meas. Tech.
ChEMBL_1930138 (CHEMBL4433389)
IC50
>100000±n/a nM
Citation
 Salerno, L; Floresta, G; Ciaffaglione, V; Gentile, D; Margani, F; Turnaturi, R; Rescifina, A; Pittalą, V Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application. Eur J Med Chem 167:439-453 (2019) [PubMed]  Article 
Target
Name:
Heme oxygenase 2
Synonyms:
1.14.14.18 | HMOX2 | HMOX2_HUMAN | HO-2 | HO2 | Heme oxygenase 2
Type:
PROTEIN
Mol. Mass.:
36025.41
Organism:
Homo sapiens
Description:
ChEMBL_11321
Residue:
316
Sequence:
MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVALAAGLLAWYYM
  
Inhibitor
Name:
BDBM50207199
Synonyms:
1-((2-(2-(4-bromophenyl)ethyl)-1,3-dioxolan-2-yl)methyl)-1H-imidazole hydrochloride | CHEMBL539857
Type:
Small organic molecule
Emp. Form.:
C15H17BrN2O2
Mol. Mass.:
337.212
SMILES:
Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1
Structure:
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