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Target
Erythropoietin receptor
Ligand
BDBM50091844
Substrate
n/a
Meas. Tech.
ChEBML_67869
IC50
30000±n/a nM
Citation
 Connolly, PJ; Wetter, SK; Murray, WV; Johnson, DL; McMahon, FJ; Farrell, FX; Tullai, J; Jolliffe, LK Synthesis and erythropoietin receptor binding affinities of N,N-disubstituted amino acids. Bioorg Med Chem Lett 10:1995-9 (2001) [PubMed]  Article 
Target
Name:
Erythropoietin receptor
Synonyms:
EPO-R | EPOR | EPOR_HUMAN
Type:
PROTEIN
Mol. Mass.:
55040.56
Organism:
Homo sapiens (Human)
Description:
ChEMBL_67864
Residue:
508
Sequence:
MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGLSDGPYSNPYENSLIPAAEPLPPSYVACS
  
Inhibitor
Name:
BDBM50091844
Synonyms:
(S)-2-(Bis-{(E)-3-[3-(4-tert-butyl-phenoxy)-phenyl]-allyl}-amino)-pentanedioic acid | CHEMBL293618
Type:
Small organic molecule
Emp. Form.:
C43H49NO6
Mol. Mass.:
675.8523
SMILES:
CC(C)(C)c1ccc(Oc2cccc(\C=C\CN(C\C=C\c3cccc(Oc4ccc(cc4)C(C)(C)C)c3)[C@@H](CCC(O)=O)C(O)=O)c2)cc1
Structure:
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