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Target
Dihydroorotase
Ligand
BDBM50536770
Substrate
n/a
Meas. Tech.
ChEMBL_1934349 (CHEMBL4480001)
Kd
67000±n/a nM
Citation
 Rice, AJ; Lei, H; Santarsiero, BD; Lee, H; Johnson, ME Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase). Bioorg Med Chem 24:4536-4543 (2016) [PubMed]  Article 
Target
Name:
Dihydroorotase
Synonyms:
Dihydroorotase (PyrC) | PYRC_BACAN | pyrC
Type:
Protein
Mol. Mass.:
46646.28
Organism:
Bacillus anthracis (Firmicute)
Description:
n/a
Residue:
428
Sequence:
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHEALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
  
Inhibitor
Name:
BDBM50536770
Synonyms:
CHEMBL4580389
Type:
Small organic molecule
Emp. Form.:
C9H14N2
Mol. Mass.:
150.2209
SMILES:
CCC1NCCn2cccc12
Structure:
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