Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50538228
Substrate
n/a
Meas. Tech.
ChEMBL_1972438 (CHEMBL4605256)
Ki
150±n/a nM
Citation
 Su, H; Zou, Y; Chen, G; Dou, H; Xie, H; Yuan, X; Zhang, X; Zhang, N; Li, M; Xu, Y Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J Med Chem 63:4090-4106 (2020) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50538228
Synonyms:
CHEMBL4642358
Type:
Small organic molecule
Emp. Form.:
C23H16ClNO2
Mol. Mass.:
373.832
SMILES:
OC(=O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2ccccc2c1
Structure:
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