Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50094589
Substrate
n/a
Meas. Tech.
ChEMBL_30143 (CHEMBL640590)
Ki
5400±n/a nM
Citation
 Hess, S; Müller, CE; Frobenius, W; Reith, U; Klotz, KN; Eger, K 7-Deazaadenines bearing polar substituents: structure-activity relationships of new A(1) and A(3) adenosine receptor antagonists. J Med Chem 43:4636-46 (2001) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM50094589
Synonyms:
5,6-Dimethyl-7-(1-phenyl-ethyl)-2-thiophen-2-yl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine | CHEMBL341573
Type:
Small organic molecule
Emp. Form.:
C20H20N4S
Mol. Mass.:
348.465
SMILES:
C[C@H](c1ccccc1)n1c(C)c(C)c2c(N)nc(nc12)-c1cccs1
Structure:
Search PDB for entries with ligand similarity: