Reaction Details Report a problem with these data
Target
Aldehyde dehydrogenase family 1 member A3
Ligand
BDBM50538685
Substrate
n/a
Meas. Tech.
ChEMBL_1973874 (CHEMBL4606692)
Ki
8700±n/a nM
Citation
 Quattrini, L; Gelardi, ELM; Petrarolo, G; Colombo, G; Ferraris, DM; Picarazzi, F; Rizzi, M; Garavaglia, S; La Motta, C Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2- ACS Med Chem Lett 11:963-970 (2020) [PubMed]  Article 
Target
Name:
Aldehyde dehydrogenase family 1 member A3
Synonyms:
Aldehyde dehydrogenase 6 | Aldehyde dehydrogenase family 1 member A3 | RALDH-3 | RalDH3 | Retinaldehyde dehydrogenase 3 | AL1A3_HUMAN | ALDH1A3 | ALDH6
Type:
PROTEIN
Mol. Mass.:
56110.85
Organism:
Human
Description:
ChEMBL_109700
Residue:
512
Sequence:
MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP
  
Inhibitor
Name:
BDBM50538685
Synonyms:
CHEMBL4644541
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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