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Target
Beta-glucuronidase
Ligand
BDBM50008907
Substrate
n/a
Meas. Tech.
ChEMBL_1978620 (CHEMBL4611755)
IC50
24300±n/a nM
Citation
 Yang, F; Zhu, W; Sun, S; Ai, Q; Edirisuriya, P; Zhou, K Isolation and Structural Characterization of Specific Bacterial ?-Glucuronidase Inhibitors from Noni ( J Nat Prod 83:825-833 (2020) [PubMed]  Article 
Target
Name:
Beta-glucuronidase
Synonyms:
β-Glucuronidase | BGLR_ECOLI | Beta-glucuronidase (EcGUS) | gurA | gusA | uidA
Type:
Protein
Mol. Mass.:
68431.57
Organism:
Escherichia coli (Enterobacteria)
Description:
P05804
Residue:
603
Sequence:
MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRAIAVPGSFNDQFADADIRNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQEVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSYFHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRDADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAVKGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCDAHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVDTLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGNKKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ
  
Inhibitor
Name:
BDBM50008907
Synonyms:
D-Saccharic Acid 1,4-Lactone
Type:
Small organic molecule
Emp. Form.:
C6H8O7
Mol. Mass.:
192.1235
SMILES:
[H][C@@]1(OC(=O)[C@H](O)[C@H]1O)[C@H](O)C(O)=O |r|
Structure:
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