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Target
N-acylethanolamine-hydrolyzing acid amidase
Ligand
BDBM50151057
Substrate
n/a
Meas. Tech.
ChEMBL_1978882 (CHEMBL4612017)
IC50
6.0±n/a nM
Citation
 Piomelli, D; Scalvini, L; Fotio, Y; Lodola, A; Spadoni, G; Tarzia, G; Mor, M -Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition. J Med Chem 63:7475-7490 (2020) [PubMed]  Article 
Target
Name:
N-acylethanolamine-hydrolyzing acid amidase
Synonyms:
ASAH-like protein | ASAHL | Acid ceramidase-like protein | N-acylethanolamine-hydrolyzing acid amidase | N-acylsphingosine amidohydrolase-like | N-acylsphingosine-amidohydrolase | NAAA | NAAA_HUMAN | PLT
Type:
Enzyme
Mol. Mass.:
40073.12
Organism:
Homo sapiens (Human)
Description:
Q02083
Residue:
359
Sequence:
MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLVRAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAYESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKTPLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDRRTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
  
Inhibitor
Name:
BDBM50151057
Synonyms:
CHEMBL3770726
Type:
Small organic molecule
Emp. Form.:
C14H24N2O3
Mol. Mass.:
268.352
SMILES:
O=C(N[C@H]1CNC1=O)OCCCCC1CCCCC1 |r|
Structure:
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