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Target
Delta-type opioid receptor
Ligand
BDBM50095733
Substrate
n/a
Meas. Tech.
ChEMBL_145765 (CHEMBL752783)
IC50
35±n/a nM
Citation
 Maeda, DY; Berman, F; Murray, TF; Aldrich, JV Synthesis and evaluation of isothiocyanate-containing derivatives of the delta-opioid receptor antagonist Tyr-Tic-Phe-Phe (TIPP) as potential affinity labels for delta-opioid receptors. J Med Chem 43:5044-9 (2001) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50095733
Synonyms:
2-[2-(2-{2-[2-Dibenzylamino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-(4-isothiocyanato-phenyl)-propionylamino]-4-methyl-pentanoic acid | CHEMBL146354
Type:
Small organic molecule
Emp. Form.:
C43H48N6O7S
Mol. Mass.:
792.942
SMILES:
CC(C)CC(NC(=O)C(Cc1ccc(cc1)N=C=S)NC(=O)CNC(=O)CNC(=O)C(Cc1ccc(O)cc1)N(Cc1ccccc1)Cc1ccccc1)C(O)=O
Structure:
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