Reaction Details Report a problem with these data
Target
Nonstructural protein 3
Ligand
BDBM13142
Substrate
n/a
Meas. Tech.
ChEMBL_1986298 (CHEMBL4619845)
Ki
140±n/a nM
Citation
 Voss, S; Nitsche, C Inhibitors of the Zika virus protease NS2B-NS3. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Nonstructural protein 3
Synonyms:
Genome polyprotein | NS3
Type:
PROTEIN
Mol. Mass.:
7653.58
Organism:
Zika virus
Description:
ChEMBL_119671
Residue:
66
Sequence:
AETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPV
  
Inhibitor
Name:
BDBM13142
Synonyms:
(2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylbutanoyl]-N-benzylpyrrolidine-2-carboxamide | JMC517169 Compound 1 | Smac AVPI Mimetic 1 | Smac peptido-mimetic 1
Type:
Small organic molecule
Emp. Form.:
C20H30N4O3
Mol. Mass.:
374.4772
SMILES:
CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1 |r|
Structure:
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