Reaction Details Report a problem with these data
Target
Nonstructural protein 3
Ligand
BDBM50542240
Substrate
n/a
Meas. Tech.
ChEMBL_1986301 (CHEMBL4619848)
EC50
22±n/a nM
Citation
 Voss, S; Nitsche, C Inhibitors of the Zika virus protease NS2B-NS3. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Nonstructural protein 3
Synonyms:
Genome polyprotein | NS3
Type:
PROTEIN
Mol. Mass.:
7653.58
Organism:
Zika virus
Description:
ChEMBL_119671
Residue:
66
Sequence:
AETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPV
  
Inhibitor
Name:
BDBM50542240
Synonyms:
EF-9 | EF9 | Foscan | Mthpc | Temoporfin
Type:
Small organic molecule
Emp. Form.:
C44H32N4O4
Mol. Mass.:
680.7493
SMILES:
Oc1cccc(c1)-c1c2CCc(n2)c(-c2cccc(O)c2)c2ccc([nH]2)c(-c2cccc(O)c2)c2ccc([nH]2)c(-c2cccc(O)c2)c2ccc1n2
Structure:
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