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Target
HTH-type quorum-sensing regulator RhlR
Ligand
BDBM50210051
Substrate
n/a
Meas. Tech.
ChEMBL_1988608 (CHEMBL4622155)
IC50
218000±n/a nM
Citation
 Nam, S; Ham, SY; Kwon, H; Kim, HS; Moon, S; Lee, JH; Lim, T; Son, SH; Park, HD; Byun, Y Discovery and Characterization of Pure RhlR Antagonists against  J Med Chem 63:8388-8407 (2020) [PubMed]  Article 
Target
Name:
HTH-type quorum-sensing regulator RhlR
Synonyms:
Elastase modulator | RHLR_PSEAE | Regulatory protein RhlR | lasM | rhlR | vsmR | vsmR
Type:
PROTEIN
Mol. Mass.:
27579.79
Organism:
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)
Description:
ChEMBL_108034
Residue:
241
Sequence:
MRNDGGFLLWWDGLRSEMQPIHDSQGVFAVLEKEVRRLGFDYYAYGVRHTIPFTRPKTEVHGTYPKAWLERYQMQNYGAVDPAILNGLRSSEMVVWSDSLFDQSRMLWNEARDWGLCVGATLPIRAPNNLLSVLSVARDQQNISSFEREEIRLRLRCMIELLTQKLTDLEHPMLMSNPVCLSHREREILQWTADGKSSGEIAIILSISESTVNFHHKNIQKKFDAPNKTLAAAYAAALGLI
  
Inhibitor
Name:
BDBM50210051
Synonyms:
CHEMBL3883439
Type:
Small organic molecule
Emp. Form.:
C15H22O4
Mol. Mass.:
266.3328
SMILES:
CCCC(O)CC(=O)CCc1ccc(O)c(OC)c1
Structure:
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