Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50188597
Substrate
n/a
Meas. Tech.
ChEMBL_1991283 (CHEMBL4625018)
Ki
>100000±n/a nM
Citation
 Pieterse, L; van der Walt, MM; Terre'Blanche, G C2-substituted quinazolinone derivatives exhibit A Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50188597
Synonyms:
CHEMBL18688
Type:
Small organic molecule
Emp. Form.:
C14H9FN2O
Mol. Mass.:
240.2325
SMILES:
Oc1nc(nc2ccccc12)-c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: