Reaction Details Report a problem with these data
Target
Calpain small subunit 1
Ligand
BDBM50101320
Substrate
n/a
Meas. Tech.
ChEBML_43685
Ki
673.0±n/a nM
Citation
 Donkor, IO; Zheng, X; Han, J; Lacy, C; Miller, DD Significance of hydrogen bonding at the S(1)' subsite of calpain I. Bioorg Med Chem Lett 11:1753-5 (2001) [PubMed]  Article 
Target
Name:
Calpain small subunit 1
Synonyms:
CANP small subunit | CAPN4 | CAPNS1 | CDPS | CPNS1_PIG | CSS1 | Calcium-activated neutral proteinase small subunit | Calcium-dependent protease small subunit | Calcium-dependent protease small subunit 1 | Calpain regulatory subunit
Type:
PROTEIN
Mol. Mass.:
28062.13
Organism:
Sus scrofa
Description:
ChEMBL_43862
Residue:
266
Sequence:
MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKQFDVDRSGTIGSSELPGAFEAAGFHLNEHLYSMIIRRYSDEGGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
  
Inhibitor
Name:
BDBM50101320
Synonyms:
CHEMBL300270 | {(S)-1-[(S)-1-Benzyl-2-(benzyloxy-methyl-carbamoyl)-2-oxo-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester
Type:
Small organic molecule
Emp. Form.:
C32H37N3O6
Mol. Mass.:
559.6527
SMILES:
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)N(C)OCc1ccccc1
Structure:
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