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Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM50118216
Substrate
n/a
Meas. Tech.
ChEMBL_1991664 (CHEMBL4625399)
Ki
13000±n/a nM
Citation
 DeSouza, SR; Olson, MC; Tinucci, SL; Sinner, EK; Flynn, RS; Marshall, QF; Jakubowski, HV; McIntee, EJ SAR of non-hydrolysable analogs of pyridoxal 5'-phosphate against low molecular weight protein tyrosine phosphatase isoforms. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM50118216
Synonyms:
(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate | CHEMBL82202 | pyridoxal 5'-(dihydrogen phosphate) | pyridoxal 5'-phosphate
Type:
Small organic molecule
Emp. Form.:
C8H10NO6P
Mol. Mass.:
247.1419
SMILES:
Cc1ncc(COP(O)(O)=O)c(C=O)c1O
Structure:
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