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Target
Beta-2 adrenergic receptor
Ligand
BDBM50545798
Substrate
n/a
Meas. Tech.
ChEMBL_1996605 (CHEMBL4630500)
IC50
1.7±n/a nM
Citation
 Duran-Corbera, A; Catena, J; Otero-Viņas, M; Llebaria, A; Rovira, X Photoswitchable Antagonists for a Precise Spatiotemporal Control of ? J Med Chem 63:8458-8470 (2020) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50545798
Synonyms:
CHEMBL4633760
Type:
Small organic molecule
Emp. Form.:
C20H26N4O3
Mol. Mass.:
370.4454
SMILES:
CC(C)NC[C@H](O)COc1ccccc1\N=N\c1ccc(NC(C)=O)cc1 |r|
Structure:
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