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Target
Glucagon receptor
Ligand
BDBM50104066
Substrate
n/a
Meas. Tech.
ChEMBL_72866 (CHEMBL683962)
IC50
4900±n/a nM
Citation
 Ling, A; Hong, Y; Gonzalez, J; Gregor, V; Polinsky, A; Kuki, A; Shi, S; Teston, K; Murphy, D; Porter, J; Kiel, D; Lakis, J; Anderes, K; May, J; Knudsen, LB; Lau, J Identification of alkylidene hydrazides as glucagon receptor antagonists. J Med Chem 44:3141-9 (2001) [PubMed]  Article 
Target
Name:
Glucagon receptor
Synonyms:
GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR)
Type:
Enzyme
Mol. Mass.:
54026.92
Organism:
Homo sapiens (Human)
Description:
P47871
Residue:
477
Sequence:
MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
  
Inhibitor
Name:
BDBM50104066
Synonyms:
4-Hydroxy-3-methoxy-benzoic acid [3-(3-trifluoromethyl-phenoxy)-benzylidene]-hydrazide | CHEMBL420290
Type:
Small organic molecule
Emp. Form.:
C22H17F3N2O4
Mol. Mass.:
430.3766
SMILES:
COc1cc(ccc1O)C(=O)N\N=C\c1cccc(Oc2cccc(c2)C(F)(F)F)c1
Structure:
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