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Target
Glucagon receptor
Ligand
BDBM50104096
Substrate
n/a
Meas. Tech.
ChEMBL_73015 (CHEMBL681694)
IC50
27±n/a nM
Citation
 Ling, A; Hong, Y; Gonzalez, J; Gregor, V; Polinsky, A; Kuki, A; Shi, S; Teston, K; Murphy, D; Porter, J; Kiel, D; Lakis, J; Anderes, K; May, J; Knudsen, LB; Lau, J Identification of alkylidene hydrazides as glucagon receptor antagonists. J Med Chem 44:3141-9 (2001) [PubMed]  Article 
Target
Name:
Glucagon receptor
Synonyms:
GL-R | GLR_RAT | Gcgr
Type:
PROTEIN
Mol. Mass.:
55053.40
Organism:
Rattus norvegicus
Description:
ChEMBL_1450588
Residue:
485
Sequence:
MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDASQCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQEGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRLADSPT
  
Inhibitor
Name:
BDBM50104096
Synonyms:
3-Chloro-4-hydroxy-benzoic acid (4-hydroxy-naphthalen-1-ylmethylene)-hydrazide | 3-Chloro-4-hydroxy-benzoic acid [1-(4-hydroxy-naphthalen-1-yl)-meth-(E)-ylidene]-hydrazide | CHEMBL107070
Type:
Small organic molecule
Emp. Form.:
C18H13ClN2O3
Mol. Mass.:
340.76
SMILES:
Oc1ccc(cc1Cl)C(=O)N\N=C\c1ccc(O)c2ccccc12
Structure:
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