Reaction Details Report a problem with these data
Target
Glutamyl-tRNA(Gln) amidotransferase subunit C
Ligand
BDBM50104433
Substrate
n/a
Meas. Tech.
ChEBML_72011
IC50
1100±n/a nM
Citation
 Decicco, CP; Nelson, DJ; Luo, Y; Shen, L; Horiuchi, KY; Amsler, KM; Foster, LA; Spitz, SM; Merrill, JJ; Sizemore, CF; Rogers, KC; Copeland, RA; Harpel, MR Glutamyl-gamma-boronate inhibitors of bacterial Glu-tRNA(Gln) amidotransferase. Bioorg Med Chem Lett 11:2561-4 (2001) [PubMed]  Article 
Target
Name:
Glutamyl-tRNA(Gln) amidotransferase subunit C
Synonyms:
GATC_STRP1 | gatC
Type:
PROTEIN
Mol. Mass.:
11062.35
Organism:
Streptococcus pyogenes serotype M1
Description:
ChEMBL_72840
Residue:
100
Sequence:
MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEVDTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA
  
Inhibitor
Name:
BDBM50104433
Synonyms:
(S)-2-Methylamino-4-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3-bora-tricyclo[6.1.1.0*1,5*]dec-3-yl)-butyric acid | CHEMBL83517
Type:
Small organic molecule
Emp. Form.:
C15H26BNO4
Mol. Mass.:
295.182
SMILES:
CN[C@@H](CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)C(O)=O
Structure:
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