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Target
Butyrophilin subfamily 3 member A1
Ligand
BDBM50547242
Substrate
n/a
Meas. Tech.
ChEMBL_2017319 (CHEMBL4670897)
EC50
0.728000±n/a nM
Citation
 Kadri, H; Taher, TE; Xu, Q; Sharif, M; Ashby, E; Bryan, RT; Willcox, BE; Mehellou, Y Aryloxy Diester Phosphonamidate Prodrugs of Phosphoantigens (ProPAgens) as Potent Activators of V?9/V?2 T-Cell Immune Responses. J Med Chem 63:11258-11270 (2020) [PubMed]  Article 
Target
Name:
Butyrophilin subfamily 3 member A1
Synonyms:
BT3A1_HUMAN | BTF5 | BTN3A1 | Butyrophilin subfamily 3 member A1 | CD_antigen=CD277
Type:
PROTEIN
Mol. Mass.:
57685.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_117363
Residue:
513
Sequence:
MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGYKDGGIHLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA
  
Inhibitor
Name:
BDBM50547242
Synonyms:
CHEMBL4764764
Type:
Small organic molecule
Emp. Form.:
C16H22F2NO5P
Mol. Mass.:
377.3201
SMILES:
COC(=O)[C@H](C)NP(=O)(Oc1ccccc1)C(F)(F)C\C=C(/C)CO |r|
Structure:
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