Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1F
Ligand
BDBM50106249
Substrate
n/a
Meas. Tech.
ChEMBL_2081 (CHEMBL616724)
Ki
3.9±n/a nM
Citation
 Russell, MG; Baker, RJ; Barden, L; Beer, MS; Bristow, L; Broughton, HB; Knowles, M; McAllister, G; Patel, S; Castro, JL N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands. J Med Chem 44:3881-95 (2001) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1F
Synonyms:
5-HT-1F | 5-HT1F | 5-hydroxytryptamine receptor 1F | 5HT1F_HUMAN | HTR1EL | HTR1F | Serotonin (5-HT) receptor | Serotonin 1f (5-HT1f) receptor | Serotonin receptor 1F
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.68
Organism:
Homo sapiens (Human)
Description:
5-HT1F HTR1F HUMAN::P30939
Residue:
366
Sequence:
MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC
  
Inhibitor
Name:
BDBM50106249
Synonyms:
CHEMBL92139 | [2-(1-Benzenesulfonyl-1H-indol-4-yl)-ethyl]-dimethyl-amine
Type:
Small organic molecule
Emp. Form.:
C18H20N2O2S
Mol. Mass.:
328.429
SMILES:
CN(C)CCc1cccc2n(ccc12)S(=O)(=O)c1ccccc1
Structure:
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