Reaction Details Report a problem with these data
Target
Integrase
Ligand
BDBM50107100
Substrate
n/a
Meas. Tech.
ChEBML_88617
IC50
157000±n/a nM
Citation
 Dupont, R; Jeanson, L; Mouscadet, JF; Cotelle, P Synthesis and HIV-1 integrase inhibitory activities of catechol and bis-catechol derivatives. Bioorg Med Chem Lett 11:3175-8 (2001) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50107100
Synonyms:
4-(1,3,7-Trimethyl-naphthalen-2-yl)-benzene-1,2-diol | CHEMBL326892
Type:
Small organic molecule
Emp. Form.:
C19H18O2
Mol. Mass.:
278.345
SMILES:
Cc1ccc2cc(C)c(-c3ccc(O)c(O)c3)c(C)c2c1
Structure:
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