Reaction Details Report a problem with these data
Target
Galactocerebrosidase
Ligand
BDBM50549786
Substrate
n/a
Meas. Tech.
ChEMBL_2025796 (CHEMBL4679609)
Ki
2300000±n/a nM
Citation
 Viuff, A; Salamone, S; McLoughlin, J; Deane, JE; Jensen, HH The Bicyclic Form of  ACS Med Chem Lett 12:56-59 (2021) [PubMed]  Article 
Target
Name:
Galactocerebrosidase
Synonyms:
3.2.1.46 | GALCERase | GALC_MOUSE | Galactocerebrosidase | Galactocerebroside beta-galactosidase | Galactosylceramidase | Galactosylceramide beta-galactosidase | Galc
Type:
PROTEIN
Mol. Mass.:
77258.04
Organism:
Mus musculus
Description:
ChEMBL_11497
Residue:
684
Sequence:
MANSQPKASQQRQAKVMTAAAGSASRVAVPLLLCALLVPGGAYVLDDSDGLGREFDGIGAVSGGGATSRLLVNYPEPYRSEILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYELDENYFRGYEWWLMKEAKKRNPDIILMGLPWSFPGWLGKGFSWPYVNLQLTAYYVVRWILGAKHYHDLDIDYIGIWNERPFDANYIKELRKMLDYQGLQRVRIIASDNLWEPISSSLLLDQELWKVVDVIGAHYPGTYTVWNAKMSGKKLWSSEDFSTINSNVGAGCWSRILNQNYINGNMTSTIAWNLVASYYEELPYGRSGLMTAQEPWSGHYVVASPIWVSAHTTQFTQPGWYYLKTVGHLEKGGSYVALTDGLGNLTIIIETMSHQHSMCIRPYLPYYNVSHQLATFTLKGSLREIQELQVWYTKLGTPQQRLHFKQLDTLWLLDGSGSFTLELEEDEIFTLTTLTTGRKGSYPPPPSSKPFPTNYKDDFNVEYPLFSEAPNFADQTGVFEYYMNNEDREHRFTLRQVLNQRPITWAADASSTISVIGDHHWTNMTVQCDVYIETPRSGGVFIAGRVNKGGILIRSATGVFFWIFANGSYRVTADLGGWITYASGHADVTAKRWYTLTLGIKGYFAFGMLNGTILWKNVRVKYPGHGWAAIGTHTFEFAQFDNFRVEAAR
  
Inhibitor
Name:
BDBM50549786
Synonyms:
CHEMBL4741914
Type:
Small organic molecule
Emp. Form.:
C8H15NO3
Mol. Mass.:
173.2096
SMILES:
[H][C@@]12CC[C@@]([H])(N1)[C@H](CO)[C@H](O)[C@@H]2O |r|
Structure:
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