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Target
Mu-type opioid receptor
Ligand
BDBM50550066
Substrate
n/a
Meas. Tech.
ChEMBL_2026352 (CHEMBL4680510)
EC50
0.017000±n/a nM
Citation
 Gutman, ES; Bow, E; Li, F; Sulima, A; Kaska, S; Crowley, R; Prisinzano, TE; Lee, YS; Hassan, SA; Imler, GH; Deschamps, JR; Jacobson, AE; Rice, KC G-Protein biased opioid agonists: 3-hydroxy- RSC Med Chem 11:896-904 (2020) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50550066
Synonyms:
CHEMBL4798954
Type:
Small organic molecule
Emp. Form.:
C22H27NO2
Mol. Mass.:
337.4553
SMILES:
[H][C@]12CCC[C@@](CCN1CCc1ccccc1)([C@@H]2O)c1cccc(O)c1 |r,THB:9:8:4.3.2:17|
Structure:
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