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Target
Cathepsin Z
Ligand
BDBM50551798
Substrate
n/a
Meas. Tech.
ChEMBL_2032362 (CHEMBL4686520)
IC50
12400±n/a nM
Citation
 Fonovi?, UP; Knez, D; Hrast, M; Zidar, N; Proj, M; Gobec, S; Kos, J Structure-activity relationships of triazole-benzodioxine inhibitors of cathepsin X. Eur J Med Chem 193:0 (2020) [PubMed]  Article 
Target
Name:
Cathepsin Z
Synonyms:
CATZ_HUMAN | CTSZ | Cathepsin P | Cathepsin X
Type:
PROTEIN
Mol. Mass.:
33870.59
Organism:
Homo sapiens (Human)
Description:
ChEMBL_595889
Residue:
303
Sequence:
MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEEHCTFGDPIV
  
Inhibitor
Name:
BDBM50551798
Synonyms:
CHEMBL4752735
Type:
Small organic molecule
Emp. Form.:
C19H14N4O3S
Mol. Mass.:
378.404
SMILES:
O=C(CSc1nncn1-c1ccc(cc1)C#N)c1ccc2OCCOc2c1
Structure:
Search PDB for entries with ligand similarity: