Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50042211
Substrate
n/a
Meas. Tech.
ChEMBL_30305 (CHEMBL636450)
Ki
34±n/a nM
Citation
 Kim, SA; Marshall, MA; Melman, N; Kim, HS; Müller, CE; Linden, J; Jacobson, KA Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. J Med Chem 45:2131-8 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50042211
Synonyms:
8-Cyclopentyl-1-propyl-3,7-dihydro-purine-2,6-dione | 8-Cyclopentyl-1-propylX | CHEMBL37243
Type:
Small organic molecule
Emp. Form.:
C13H18N4O2
Mol. Mass.:
262.3076
SMILES:
CCCn1c(=O)[nH]c2nc([nH]c2c1=O)C1CCCC1
Structure:
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