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Target
Prolactin-releasing peptide receptor
Ligand
BDBM50553336
Substrate
n/a
Meas. Tech.
ChEMBL_2046262 (CHEMBL4700961)
EC50
13±n/a nM
Citation
 Pflimlin, E; Lear, S; Lee, C; Yu, S; Zou, H; To, A; Joseph, S; Nguyen-Tran, V; Tremblay, MS; Shen, W Design of a Long-Acting and Selective MEG-Fatty Acid Stapled Prolactin-Releasing Peptide Analog. ACS Med Chem Lett 10:1166-1172 (2019) [PubMed]  Article 
Target
Name:
Prolactin-releasing peptide receptor
Synonyms:
G-protein coupled receptor 10 (GPR10) | GPR10 | GR3 | PRLHR | PRLHR_HUMAN | Prolactin Releasing Peptide Receptor | Prolactin-releasing peptide receptor
Type:
Protein
Mol. Mass.:
41138.32
Organism:
Homo sapiens (Human)
Description:
P49683
Residue:
370
Sequence:
MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVIVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPHGQNMTVSVVI
  
Inhibitor
Name:
BDBM50553336
Synonyms:
CHEMBL4760676
Type:
Small organic molecule
Emp. Form.:
C153H240N52O43S2
Mol. Mass.:
3559.995
SMILES:
CCCC[C@@H]1NC(=O)[C@H](CO)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC1=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)CC(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CO |r|
Structure:
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