Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50553401
Substrate
n/a
Meas. Tech.
ChEMBL_2046305 (CHEMBL4701004)
Ki
1.7±n/a nM
Citation
 Yu, F; Zhu, C; Xie, Q; Wang, Y Adenosine A J Med Chem 63:12196-12212 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50553401
Synonyms:
CHEMBL4778265
Type:
Small organic molecule
Emp. Form.:
C19H21N5O4
Mol. Mass.:
383.4011
SMILES:
C[C@H](O)COc1nc(nc(N)c1C(=O)NCc1ncccc1C)-c1ccco1 |r|
Structure:
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