Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50554598
Substrate
n/a
Meas. Tech.
ChEMBL_2050013 (CHEMBL4704712)
EC50
2188±n/a nM
Citation
 Xu, F; Zhao, Y; Zhou, H; Li, C; Zhang, X; Hou, T; Qu, L; Wei, L; Wang, J; Liu, Y; Liang, X Synthesis and evaluation of 3-(4-(phenoxymethyl)phenyl)propanoic acid and N-phenylbenzenesulfonamide derivatives as FFA4 agonists. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4 | Synonyms=GPR120
Type:
PROTEIN
Mol. Mass.:
40511.04
Organism:
Homo sapiens
Description:
ChEMBL_100956
Residue:
361
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50554598
Synonyms:
CHEMBL4744629
Type:
Small organic molecule
Emp. Form.:
C14H13F3N2O2S
Mol. Mass.:
330.325
SMILES:
Cc1ccc(cc1)S(=O)(=O)Nc1ccc(N)c(c1)C(F)(F)F
Structure:
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