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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50383373
Substrate
n/a
Meas. Tech.
ChEMBL_2051742 (CHEMBL4706441)
Ki
4.6±n/a nM
Citation
 An, S; Kim, G; Kim, HJ; Ahn, S; Kim, HY; Ko, H; Hyun, YE; Nguyen, M; Jeong, J; Liu, Z; Han, J; Choi, H; Yu, J; Kim, JW; Lee, HW; Jacobson, KA; Cho, WJ; Kim, YM; Kang, KW; Noh, M; Jeong, LS Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPAR?/? Modulators. J Med Chem 63:16012-16027 (2020) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50383373
Synonyms:
CHEMBL592652 | GSK0660
Type:
Small organic molecule
Emp. Form.:
C19H18N2O5S2
Mol. Mass.:
418.487
SMILES:
COC(=O)c1sccc1S(=O)(=O)Nc1ccc(Nc2ccccc2)cc1OC
Structure:
Search PDB for entries with ligand similarity: