Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50059375
Substrate
n/a
Meas. Tech.
ChEMBL_27904 (CHEMBL640564)
Ki
>10000±n/a nM
Citation
 Okamura, T; Kurogi, Y; Nishikawa, H; Hashimoto, K; Fujiwara, H; Nagao, Y 1,2,4-Triazolo[5,1-i]purine derivatives as highly potent and selective human adenosine A(3) receptor ligands. J Med Chem 45:3703-8 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50059375
Synonyms:
5-Amino-3-(4-methoxy-phenyl)-thiazolo[3,2-a]pyrimidin-7-one | CHEMBL89472
Type:
Small organic molecule
Emp. Form.:
C13H11N3O2S
Mol. Mass.:
273.31
SMILES:
COc1ccc(cc1)-c1csc2nc(=O)cc(N)n12
Structure:
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