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Target
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D
Ligand
BDBM31712
Substrate
n/a
Meas. Tech.
ChEMBL_2057750 (CHEMBL4712751)
IC50
11000±n/a nM
Citation
 Mock, ED; Kotsogianni, I; Driever, WPF; Fonseca, CS; Vooijs, JM; den Dulk, H; van Boeckel, CAA; van der Stelt, M Structure-Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of  J Med Chem 64:481-515 (2021) [PubMed]  Article 
Target
Name:
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D
Synonyms:
3.1.4.54 | Mbldc1 | N-acyl phosphatidylethanolamine phospholipase D | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | NAPE-PLD | NAPE-hydrolyzing phospholipase D | NAPEP_MOUSE | Napepld
Type:
PROTEIN
Mol. Mass.:
45810.25
Organism:
Mus musculus
Description:
ChEMBL_105212
Residue:
396
Sequence:
MDEYEDSQSPAPSYQYPKETLRKRQNSVQNSGGSVSSRFSRKSFKLDYRLEEDVTKSKKGKDGRFVNPWPTWKNISIPNVLRWLIMEKNHSGVPGSKEELDKELPVLKPYFVSDPEDAGVREAGLRVTWLGHATLMVEMDELIFLTDPMFSSRASPSQYMGPKRFRRPPCTISELPTIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLLDDNKVLWGSWSVLGPWSRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHADPEDAVRIHIDLQTKRSVAIHWGTFALANEHYLEPPVKLNEALERYGLSCEDFFILKHGESRYLNTDDRAFEET
  
Inhibitor
Name:
BDBM31712
Synonyms:
HEXACHLOROPHENE | Hexach-lorophene | MLS000028433 | SMR000058356 | cid_3598
Type:
Small organic molecule
Emp. Form.:
C13H6Cl6O2
Mol. Mass.:
406.904
SMILES:
Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl
Structure:
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