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Target
Actin, alpha skeletal muscle
Ligand
BDBM50558159
Substrate
n/a
Meas. Tech.
ChEMBL_2062022 (CHEMBL4717275)
Kd
13±n/a nM
Citation
 Hirayama, Y; Yamagishi, K; Suzuki, T; Kawagishi, H; Kita, M; Kigoshi, H Analysis of the aplyronine A-induced protein-protein interaction between actin and tubulin by surface plasmon resonance. Bioorg Med Chem 24:2809-14 (2016) [PubMed]  Article 
Target
Name:
Actin, alpha skeletal muscle
Synonyms:
ACTA | ACTA1 | ACTS_RABIT | Actin, alpha skeletal muscle | Actin, alpha skeletal muscle, intermediate form | Alpha-actin-1
Type:
PROTEIN
Mol. Mass.:
42042.02
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_119010
Residue:
377
Sequence:
MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
  
Inhibitor
Name:
BDBM50558159
Synonyms:
CHEMBL4282474
Type:
Small organic molecule
Emp. Form.:
C52H74N4O17
Mol. Mass.:
1027.1606
SMILES:
COC[C@@H](OC)C(=O)O[C@H](CC[C@H](C)[C@H](C[C@@H]1OC(=O)C[C@@H](O)C\C=C\C(=O)[C@H](C)[C@H](OC)c2coc(n2)-c2coc(n2)-c2coc(\C=C\C[C@H](OC)[C@H]1C)n2)OC)[C@H](C)[C@H](OC(C)=O)[C@H](C)\C=C\N(C)C=O |r,t:24,49|
Structure:
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