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Target
P2Y purinoceptor 6
Ligand
BDBM50558932
Substrate
n/a
Meas. Tech.
ChEMBL_2067094 (CHEMBL4722347)
IC50
6190±n/a nM
Citation
 Pillaiyar, T; Funke, M; Al-Hroub, H; Weyler, S; Ivanova, S; Schlegel, J; Abdelrahman, A; Müller, CE Design, synthesis and biological evaluation of suramin-derived dual antagonists of the proinflammatory G protein-coupled receptors P2Y Eur J Med Chem 186:0 (2020) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6_RAT | P2ry6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36704.21
Organism:
Rattus norvegicus
Description:
ChEMBL_805344
Residue:
328
Sequence:
MERDNGTIQAPGLPPTTCVYREDFKRLLLPPVYSVVLVVGLPLNVCVIAQICASRRTLTRSAVYTLNLALADLLYACSLPLLIYNYARGDHWPFGDLACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWVVCGVVWLVVTAQCLPTAVFAATGIQRNRTVCYDLSPPILSTRYLPYGMALTVIGFLLPFTALLACYCRMARRLCRQDGPAGPVAQERRSKAARMAVVVAAVFVISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASANSVLDPILFYFTQQKFRRQPHDLLQKLTAKWQRQRV
  
Inhibitor
Name:
BDBM50558932
Synonyms:
CHEMBL4780920
Type:
Small organic molecule
Emp. Form.:
C20H16N2O6S
Mol. Mass.:
412.416
SMILES:
Cc1cccc(c1)C(=O)Nc1ccc(cc1)S(=O)(=O)Oc1cccc(c1)[N+]([O-])=O
Structure:
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