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Target
DNA-3-methyladenine glycosylase
Ligand
BDBM50559764
Substrate
n/a
Meas. Tech.
ChEMBL_2070259 (CHEMBL4725793)
IC50
157000±n/a nM
Citation
 Mas Claret, E; Al Yahyaei, B; Chu, S; Elliott, RM; Imperato, M; Lopez, A; Meira, LB; Howlin, BJ; Whelligan, DK An aza-nucleoside, fragment-like inhibitor of the DNA repair enzyme alkyladenine glycosylase (AAG). Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
DNA-3-methyladenine glycosylase
Synonyms:
3-alkyladenine DNA glycosylase | 3-methyladenine DNA glycosidase | ADPG | N-methylpurine-DNA glycosylase | 3MG_HUMAN | MPG | AAG | ANPG | MID1
Type:
PROTEIN
Mol. Mass.:
32883.92
Organism:
Human
Description:
ChEMBL_109564
Residue:
298
Sequence:
MVTPALQMKKPKQFCRRMGQKKQRPARAGQPHSSSDAAQAPAEQPHSSSDAAQAPCPRERCLGPPTTPGPYRSIYFSSPKGHLTRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGRIVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYIIYGMYFCMNISSQGDGACVLLRALEPLEGLETMRQLRSTLRKGTASRVLKDRELCSGPSKLCQALAINKSFDQRDLAQDEAVWLERGPLEPSEPAVVAAARVGVGHAGEWARKPLRFYVRGSPWVSVVDRVAEQDTQA
  
Inhibitor
Name:
BDBM50559764
Synonyms:
CHEMBL4751946
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: