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Target
Mu-type opioid receptor
Ligand
BDBM50125997
Substrate
n/a
Meas. Tech.
ChEBML_146972
IC50
20±n/a nM
Citation
 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Dermorphin tetrapeptide analogues with 2',6'-dimethylphenylalanine (Dmp) substituted for aromatic amino acids have high mu opioid receptor binding and biological activities. Bioorg Med Chem Lett 13:1269-72 (2003) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50125997
Synonyms:
(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(R)-1-(2-carbamoyl-ethylcarbamoyl)-2-(2,6-dimethyl-phenyl)-ethyl]-amide | CHEMBL23133
Type:
Small organic molecule
Emp. Form.:
C29H42N8O5
Mol. Mass.:
582.6944
SMILES:
Cc1cccc(C)c1C[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCCC(N)=O
Structure:
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