Reaction Details Report a problem with these data
Target
Glutathione S-transferase Mu 2
Ligand
BDBM50562988
Substrate
n/a
Meas. Tech.
ChEMBL_2081214 (CHEMBL4737005)
IC50
160±n/a nM
Citation
 Liu, Q; Liu, Z; Hua, W; Gou, S Discovery of 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol Derivatives as Glutathione Transferase Inhibitors with Favorable Selectivity and Tolerated Toxicity. J Med Chem 64:1701-1712 (2021) [PubMed]  Article 
Target
Name:
Glutathione S-transferase Mu 2
Synonyms:
GST class-mu 2 | GST4 | GSTM2 | GSTM2-2 | GSTM2_HUMAN | Glutathione S-transferase Mu 2
Type:
PROTEIN
Mol. Mass.:
25743.85
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1441153
Residue:
218
Sequence:
MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
  
Inhibitor
Name:
BDBM50562988
Synonyms:
CHEMBL4764480
Type:
Small organic molecule
Emp. Form.:
C20H29N5O6S
Mol. Mass.:
467.539
SMILES:
CN(C)CCNC(=O)CCC(=O)OCCCCCCSc1ccc([N+]([O-])=O)c2nonc12
Structure:
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