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Target
Glutathione S-transferase Mu 2
Ligand
BDBM50562989
Substrate
n/a
Meas. Tech.
ChEMBL_2081214 (CHEMBL4737005)
IC50
100±n/a nM
Citation
 Liu, Q; Liu, Z; Hua, W; Gou, S Discovery of 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol Derivatives as Glutathione Transferase Inhibitors with Favorable Selectivity and Tolerated Toxicity. J Med Chem 64:1701-1712 (2021) [PubMed]  Article 
Target
Name:
Glutathione S-transferase Mu 2
Synonyms:
GST class-mu 2 | GST4 | GSTM2 | GSTM2-2 | GSTM2_HUMAN | Glutathione S-transferase Mu 2
Type:
PROTEIN
Mol. Mass.:
25743.85
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1441153
Residue:
218
Sequence:
MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
  
Inhibitor
Name:
BDBM50562989
Synonyms:
CHEMBL4742105
Type:
Small organic molecule
Emp. Form.:
C22H31N5O7S
Mol. Mass.:
509.576
SMILES:
[O-][N+](=O)c1ccc(SCCCCCCOC(=O)CCC(=O)NCCN2CCOCC2)c2nonc12
Structure:
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