Reaction Details Report a problem with these data
Target
Hypoxanthine-guanine phosphoribosyltransferase
Ligand
BDBM50128871
Substrate
n/a
Meas. Tech.
ChEMBL_90368 (CHEMBL697044)
Ki
600±n/a nM
Citation
 Medrano, FJ; Wenck, MA; Engel, JC; Craig, SP Analysis of 6-(2,2-Dichloroacetamido)chrysene interaction with the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi. J Med Chem 46:2548-50 (2003) [PubMed]  Article 
Target
Name:
Hypoxanthine-guanine phosphoribosyltransferase
Synonyms:
HGPRT | HGPRTase | HPRT | HPRT1 | HPRT_HUMAN | Hypoxanthine-guanine phosphoribosyltransferase | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
Type:
Protein
Mol. Mass.:
24579.61
Organism:
Homo sapiens (Human)
Description:
P00492
Residue:
218
Sequence:
MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
  
Inhibitor
Name:
BDBM50128871
Synonyms:
CHEMBL313154 | Chrysen-6-ylamine
Type:
Small organic molecule
Emp. Form.:
C18H13N
Mol. Mass.:
243.3025
SMILES:
Nc1cc2c3ccccc3ccc2c2ccccc12
Structure:
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