Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 1
Ligand
BDBM50037573
Substrate
n/a
Meas. Tech.
ChEMBL_2090954 (CHEMBL4772217)
Ki
25±n/a nM
Citation
 Nguyen, T; Marusich, J; Li, JX; Zhang, Y Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. J Med Chem 63:12387-12402 (2020) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 1
Synonyms:
G-protein coupled receptor 147 | Gpr147 | NPFF1_RAT | Neuropeptide FF receptor 1 | Npff1 | Npffr1 | RFamide-related peptide receptor OT7T022
Type:
PROTEIN
Mol. Mass.:
48338.68
Organism:
Rattus norvegicus
Description:
ChEMBL_10681
Residue:
432
Sequence:
MEAEPSQPPNGSWPLGQNGSDVETSMATSLTFSSYYQHSSPVAAMFIAAYVLIFLLCMVGNTLVCFIVLKNRHMRTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALFTIAVIWALALLIMCPSAVTLTVTREEHHFMLDARNRSYPLYSCWEAWPEKGMRKVYTAVLFAHIYLVPLALIVVMYVRIARKLCQAPGPARDTEEAVAEGGRTSRRRARVVHMLVMVALFFTLSWLPLWVLLLLIDYGELSELQLHLLSVYAFPLAHWLAFFHSSANPIIYGYFNENFRRGFQAAFRAQLCWPPWAAHKQAYSERPNRLLRRRVVVDVQPSDSGLPSESGPSSGVPGPGRLPLRNGRVAHQDGPGEGPGCNHMPLTIPAWNI
  
Inhibitor
Name:
BDBM50037573
Synonyms:
(S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentanedioic acid 5-amide 1-{[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide} | CHEMBL326770
Type:
Small organic molecule
Emp. Form.:
C25H39N9O5
Mol. Mass.:
545.6345
SMILES:
NC(=O)CC[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Structure:
Search PDB for entries with ligand similarity: