Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50130672
Substrate
n/a
Meas. Tech.
ChEMBL_152207 (CHEMBL758926)
EC50
>100000±n/a nM
Citation
 Chong, Y; Gumina, G; Mathew, JS; Schinazi, RF; Chu, CK l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance. J Med Chem 46:3245-56 (2003) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50130672
Synonyms:
(+)-1-(4-Fluoro-5-hydroxymethyl-2,5-dihydro-furan-2-yl)-4-hydroxy-1H-pyrimidin-2-one | CHEMBL113361
Type:
Small organic molecule
Emp. Form.:
C9H9FN2O4
Mol. Mass.:
228.1772
SMILES:
OCC1O[C@@H](C=C1F)n1ccc(=O)[nH]c1=O |c:5|
Structure:
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