Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50409718
Substrate
n/a
Meas. Tech.
ChEMBL_152207 (CHEMBL758926)
EC50
8800±n/a nM
Citation
 Chong, Y; Gumina, G; Mathew, JS; Schinazi, RF; Chu, CK l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance. J Med Chem 46:3245-56 (2003) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50409718
Synonyms:
CHEMBL2112118
Type:
Small organic molecule
Emp. Form.:
C9H10F3N3O3
Mol. Mass.:
265.1892
SMILES:
Nc1nc(=O)n(cc1F)[C@@H]1CC(F)(F)[C@H](CO)O1
Structure:
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