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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50566799
Substrate
n/a
Meas. Tech.
ChEMBL_2101865 (CHEMBL4810261)
IC50
3.2±n/a nM
Citation
 Mesiti, F; Gaspar, A; Chavarria, D; Maruca, A; Rocca, R; Gil Martins, E; Barreiro, S; Silva, R; Fernandes, C; Gul, S; Keminer, O; Alcaro, S; Borges, F Mapping Chromone-3-Phenylcarboxamide Pharmacophore:  J Med Chem 64:11169-11182 (2021) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50566799
Synonyms:
CHEMBL1470839
Type:
Small organic molecule
Emp. Form.:
C16H11Cl2NO2
Mol. Mass.:
320.17
SMILES:
Clc1ccc(NC(=O)C2=Cc3ccccc3OC2)cc1Cl |t:8|
Structure:
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