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Target
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Ligand
BDBM50566954
Substrate
n/a
Meas. Tech.
ChEMBL_2102069 (CHEMBL4810465)
Kd
64000±n/a nM
Citation
 Blain, JM; Grote, DL; Watkins, SM; Goshu, GM; Muller, C; Gorman, JL; Ranieri, G; Walter, RL; Hofstetter, H; Horn, JR; Hagen, TJ Structural and biophysical characterization of the Burkholderia pseudomallei IspF inhibitor L-tryptophan hydroxamate. Bioorg Med Chem Lett 48:0 (2021) [PubMed]  Article 
Target
Name:
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Synonyms:
ISPF_BURPS | MECDP-synthase | MECPP-synthase | MECPS | ispF | mecS
Type:
PROTEIN
Mol. Mass.:
17174.90
Organism:
Burkholderia pseudomallei (strain K96243)
Description:
ChEMBL_107981
Residue:
162
Sequence:
MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA
  
Inhibitor
Name:
BDBM50566954
Synonyms:
CHEMBL4874588
Type:
Small organic molecule
Emp. Form.:
C11H13N3O2
Mol. Mass.:
219.2398
SMILES:
N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r|
Structure:
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