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Target
5-hydroxytryptamine receptor 5A
Ligand
BDBM50132096
Substrate
n/a
Meas. Tech.
ChEMBL_3584 (CHEMBL620717)
Ki
100±n/a nM
Citation
 Khorana, N; Smith, C; Herrick-Davis, K; Purohit, A; Teitler, M; Grella, B; Dukat, M; Glennon, RA Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors. J Med Chem 46:3930-7 (2003) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 5A
Synonyms:
5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:
Enzyme
Mol. Mass.:
40266.25
Organism:
Homo sapiens (Human)
Description:
P47898
Residue:
357
Sequence:
MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
  
Inhibitor
Name:
BDBM50132096
Synonyms:
5-Ethyl-2-(3-phenoxy-propyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | CHEMBL128099
Type:
Small organic molecule
Emp. Form.:
C22H26N2O
Mol. Mass.:
334.4546
SMILES:
CCn1c2CCN(CCCOc3ccccc3)Cc2c2ccccc12
Structure:
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