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Target
Inositol-trisphosphate 3-kinase A
Ligand
BDBM50221514
Substrate
n/a
Meas. Tech.
ChEMBL_90112 (CHEMBL873229)
IC50
>100000±n/a nM
Citation
 Kwon, YU; Im, J; Choi, G; Kim, YS; Choi, KY; Chung, SK Synthesis of three enantiomeric pairs of scyllo-inositol phosphate and molecular interactions between all possible regioisomers of scyllo-inositol phosphate and inositol 1,4,5-trisphosphate 3-kinase. Bioorg Med Chem Lett 13:2981-4 (2003) [PubMed]  Article 
Target
Name:
Inositol-trisphosphate 3-kinase A
Synonyms:
IP3KA_RAT | Itpka
Type:
PROTEIN
Mol. Mass.:
50877.10
Organism:
Rattus norvegicus
Description:
ChEMBL_90112
Residue:
459
Sequence:
MTLPGHPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEEDVAPASPGPPDREGNWLPAAGSHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGISSSTTLGFRIEGIKKADGSCSTDFKTTRSREQVTRVFEEFMQGDAEVLKRYLNRLQQIRDTLEISDFFRRHEVIGSSLLFVHDHCHRAGVWLIDFGKTTPLPDGQILDHRRPWEEGNREDGYLLGLDNLIGILANLAER
  
Inhibitor
Name:
BDBM50221514
Synonyms:
CHEMBL3351092
Type:
Small organic molecule
Emp. Form.:
C6H16O18P4
Mol. Mass.:
500.0755
SMILES:
O[C@@H]1[C@@H](O)[C@@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O |r|
Structure:
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