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Target
Kappa-type opioid receptor
Ligand
BDBM50292340
Substrate
n/a
Meas. Tech.
ChEMBL_2106129 (CHEMBL4814804)
EC50
39811±n/a nM
Citation
 Creed, SM; Gutridge, AM; Argade, MD; Hennessy, MR; Friesen, JB; Pauli, GF; van Rijn, RM; Riley, AP Isolation and Pharmacological Characterization of Six Opioidergic  J Nat Prod 84:71-80 (2021) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50292340
Synonyms:
AKUAMMICINE | CHEMBL508955
Type:
Small organic molecule
Emp. Form.:
C20H22N2O2
Mol. Mass.:
322.4009
SMILES:
COC(=O)C1[C@H]2C[C@@H]3N(CC[C@]33C1=Nc1ccccc31)C\C2=C\C |r,t:14|
Structure:
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