Reaction Details Report a problem with these data
Target
Galectin-4
Ligand
BDBM50572252
Substrate
n/a
Meas. Tech.
ChEMBL_2116634 (CHEMBL4825575)
Kd
3200000±n/a nM
Citation
 Hassan, M; Baussière, F; Guzelj, S; Sundin, AP; Håkansson, M; Kova?i?, R; Leffler, H; Toma?i?, T; Anderluh, M; Jakopin, ?; Nilsson, UJ Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain. ACS Med Chem Lett 12:1745-1752 (2021) [PubMed]  Article 
Target
Name:
Galectin-4
Synonyms:
Antigen NY-CO-27 | Gal-4 | L-36 lactose-binding protein | L36LBP | LEG4_HUMAN | LGALS4 | Lactose-binding lectin 4
Type:
PROTEIN
Mol. Mass.:
35952.28
Organism:
Homo sapiens (Human)
Description:
ChEMBL_716454
Residue:
323
Sequence:
MAYVPAPGYQPTYNPTLPYYQPIPGGLNVGMSVYIQGVASEHMKRFFVNFVVGQDPGSDVAFHFNPRFDGWDKVVFNTLQGGKWGSEERKRSMPFKKGAAFELVFIVLAEHYKVVVNGNPFYEYGHRLPLQMVTHLQVDGDLQLQSINFIGGQPLRPQGPPMMPPYPGPGHCHQQLNSLPTMEGPPTFNPPVPYFGRLQGGLTARRTIIIKGYVPPTGKSFAINFKVGSSGDIALHINPRMGNGTVVRNSLLNGSWGSEEKKITHNPFGPGQFFDLSIRCGLDRFKVYANGQHLFDFAHRLSAFQRVDTLEIQGDVTLSYVQI
  
Inhibitor
Name:
BDBM50572252
Synonyms:
CHEMBL4855576
Type:
Small organic molecule
Emp. Form.:
C16H18N2O6
Mol. Mass.:
334.3239
SMILES:
COC(=O)c1ccc2nc(CO[C@@H]3C=CO[C@H](CO)[C@@H]3O)[nH]c2c1 |r,c:13|
Structure:
Search PDB for entries with ligand similarity: