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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50138294
Substrate
n/a
Meas. Tech.
ChEBML_105990
IC50
>10000±n/a nM
Citation
 Xi, N; Hale, C; Kelly, MG; Norman, MH; Stec, M; Xu, S; Baumgartner, JW; Fotsch, C Synthesis of novel melanocortin 4 receptor agonists and antagonists containing a succinamide core. Bioorg Med Chem Lett 14:377-81 (2003) [PubMed]  Article 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r
Type:
PROTEIN
Mol. Mass.:
35238.60
Organism:
Mus musculus
Description:
ChEMBL_1498846
Residue:
315
Sequence:
MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIAITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDVLICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITYYKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAATLTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRSQELRMTLKEVLLCSW
  
Inhibitor
Name:
BDBM50138294
Synonyms:
4-((S)-3-(4-Chloro-benzyl)-4-{4-[2-(2-cyclopropyl-1-methanesulfonyl-ethyl)-phenyl]-piperazin-1-yl}-4-oxo-butyryl)-piperazine-1-carboxylic acid tert-butyl ester | CHEMBL332442
Type:
Small organic molecule
Emp. Form.:
C35H48ClN5O6S
Mol. Mass.:
702.304
SMILES:
CC(C)(C)OC(=O)N1CCN(CC1)C(=O)C[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1N(CC1CC1)S(C)(=O)=O
Structure:
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