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Target
Adenosine receptor A2a
Ligand
BDBM50139713
Substrate
n/a
Meas. Tech.
ChEMBL_31372 (CHEMBL644664)
Ki
20±n/a nM
Citation
 Alanine, A; Anselm, L; Steward, L; Thomi, S; Vifian, W; Groaning, MD Synthesis and SAR evaluation of 1,2,4-triazoles as A(2A) receptor antagonists. Bioorg Med Chem Lett 14:817-21 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50139713
Synonyms:
3-(3,4-Dimethyl-benzyl)-5-(3-methoxy-phenyl)-1H-[1,2,4]triazole | 3-(3,4-dimethylbenzyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole | CHEMBL165760
Type:
Small organic molecule
Emp. Form.:
C18H19N3O
Mol. Mass.:
293.363
SMILES:
COc1cccc(c1)-c1nnc(Cc2ccc(C)c(C)c2)[nH]1
Structure:
Search PDB for entries with ligand similarity: